6WB2

+3 extended HIV-1 reverse transcriptase initiation complex core (displaced state)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C	HIV-1 viral RNA genome fragment	polymer	101	32623.5	1	GenBank (60651827)	Human immunodeficiency virus 1
2	D	tRNA lysine 3	polymer	79	25354.1	1		Homo sapiens
3	A	Reverse transcriptase/ribonuclease H	polymer	570	65558.3	1	UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) UniProt (by SIFTS) (P04585) In PDB	Human immunodeficiency virus 1 (HIV-1)
4	B	reverse transcriptase p51 subunit	polymer	442	51585.3	1	UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) UniProt (by SIFTS) (P04585) In PDB	Human immunodeficiency virus 1 (HIV-1)

Sequence modifications

A: 1 - 560 (UniProt: P03366)

PDB	External Database	Details
Met -1	-	expression tag
Val 0	-	expression tag
Cys 258	Gln 857	engineered mutation
Ser 280	Cys 879	engineered mutation
Gln 478	Glu 1077	engineered mutation
Asp 561	-	expression tag
Leu 562	-	expression tag
Gly 563	-	expression tag
Thr 564	-	expression tag
Leu 565	-	expression tag
Val 566	-	expression tag
Pro 567	-	expression tag
Arg 568	-	expression tag

B: 1 - 440 (UniProt: P03366)

PDB	External Database	Details
Met -1	-	expression tag
Val 0	-	expression tag
Ser 280	Cys 879	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	175121.2
All*	Total formula weight	175121.2

*Water molecules are not included.