6WAZ
+1 extended HIV-1 reverse transcriptase initiation complex core (pre-translocation state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Reverse transcriptase/ribonuclease H | polymer | 562 | 64705.3 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | Human immunodeficiency virus 1 (HIV-1) | Pr160Gag-Pol |
| 2 | B | Reverse transcriptase p51 subunit | polymer | 442 | 51585.3 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) UniProt (by SIFTS) (P04585) In PDB | Human immunodeficiency virus 1 (HIV-1) | |
| 3 | C | HIV-1 viral RNA genome fragment | polymer | 101 | 32623.5 | 1 | GenBank (60651827) | Human immunodeficiency virus 1 | |
| 4 | D | tRNA lysine 3 | polymer | 77 | 24720.7 | 1 | Homo sapiens |
Sequence modifications
A: 1 - 560 (UniProt: P03366)
B: 1 - 440 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | expression tag |
| Val 0 | - | expression tag |
| Cys 258 | Gln 857 | engineered mutation |
| Ser 280 | Cys 879 | conflict |
| Gln 478 | Glu 1077 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | expression tag |
| Val 0 | - | expression tag |
| Ser 280 | Cys 879 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 173634.8 | |
| All* | Total formula weight | 173634.8 |
