6WAY
C-terminal SH2 domain of p120RasGAP in complex with p190RhoGAP phosphotyrosine peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ras GTPase-activating protein 1 | polymer | 107 | 12467.9 | 1 | UniProt (P20936) Pfam (PF00017) | Homo sapiens (Human) | RasGAP,Ras p21 protein activator,p120GAP |
| 2 | B (V) | Rho GTPase-activating protein 35 | polymer | 10 | 1015.0 | 1 | UniProt (Q9NRY4) | Homo sapiens | Glucocorticoid receptor DNA-binding factor 1,Glucocorticoid receptor repression factor 1,GRF-1,Rho GAP p190A,p190-A |
| 3 | C, D (A, V) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A: 340 - 444 (UniProt: P20936)
V: 1086 - 1093 (UniProt: Q9NRY4)
| PDB | External Database | Details |
|---|---|---|
| Gly 338 | - | expression tag |
| Ser 339 | - | expression tag |
| Ser 372 | Cys 372 | engineered mutation |
| Ser 402 | Cys 402 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ace 1085 | - | acetylation |
| Nh2 1094 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13482.9 | |
| All* | Total formula weight | 13482.9 |
