6W9U

Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H-Ac-6-FP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Major histocompatibility complex class I-related gene protein	polymer	271	31692.6	2	UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) In PDB	Homo sapiens (Human)	MHC class I-related gene protein,Class I histocompatibility antigen-like protein
2	B, F	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	D, G	TCR-alpha chain	polymer	204	22781.3	2		Homo sapiens (Human)
4	E, H	TCR-beta chain	polymer	246	27677.8	2		Homo sapiens (Human)
5	A, C	1-[[6-(1-$l^{1}-oxidanylethyl)-4-$l^{3}-oxidanylidene-2,3,6,8~{a}-tetrahydropteridin-2-yl]-$l^{2}-azanyl]ethanone	non-polymer		247.2	2	Chemie (TKG)
6	A, C, F	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
7	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
8		water	water		18.0	1465	Chemie (HOH)

Sequence modifications

A, C: 1 - 270 (UniProt: Q95460)

PDB	External Database	Details
Met 0	-	expression tag
His 9	Arg 31	engineered mutation
Ser 261	Cys 283	conflict

B, F: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	188062.0
Non-Polymers*	Number of molecules	7
	Total formula weight	898.2
All*	Total formula weight	188960.3

*Water molecules are not included.