6W83

K2P2.1 (TREK-1), 100 mM K+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Potassium channel subfamily K member 2	polymer	312	34303.9	2	UniProt (P97438) Pfam (PF07885) In PDB	Mus musculus (Mouse)	Outward rectifying potassium channel protein TREK-1,TREK-1 K(+) channel subunit,Two pore potassium channel TPKC1
2	A, B	CADMIUM ION	non-polymer		112.4	3	Chemie (CD)
3	A	DODECANE	non-polymer		170.3	2	Chemie (D12)
4	A, B	N-OCTANE	non-polymer		114.2	3	Chemie (OCT)
5	A, B	POTASSIUM ION	non-polymer		39.1	6	Chemie (K)
6	A	HEXADECANE	non-polymer		226.4	1	Chemie (R16)
7	B	DECANE	non-polymer		142.3	1	Chemie (D10)

Sequence modifications

A, B: 21 - 322 (UniProt: P97438)

PDB	External Database	Details
Met 20	-	expression tag
Arg 84	Lys 99	engineered mutation
Glu 85	Gln 100	engineered mutation
Lys 86	Thr 101	engineered mutation
Leu 88	Ile 103	engineered mutation
Arg 89	Ala 104	engineered mutation
Ala 90	Gln 105	engineered mutation
Pro 92	Ala 107	engineered mutation
Ser 95	Asn 110	engineered mutation
Asp 96	Ser 111	engineered mutation
Gln 97	Thr 112	engineered mutation
Ala 119	Asn 134	engineered mutation
Ala 300	Ser 315	engineered mutation
Ala 306	Glu 321	engineered mutation
Ser 323	-	expression tag
Asn 324	-	expression tag
Ser 325	-	expression tag
Leu 326	-	expression tag
Glu 327	-	expression tag
Val 328	-	expression tag
Leu 329	-	expression tag
Phe 330	-	expression tag
Gln 331	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68607.9
Non-Polymers*	Number of molecules	16
	Total formula weight	1623.9
All*	Total formula weight	70231.8

*Water molecules are not included.