6W7H
Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Nonstructural polyprotein | polymer | 168 | 18518.9 | 4 | UniProt (A0A4D6GPC4) Pfam (PF01661) UniProt (by SIFTS) (Q8JUX6) In PDB | Chikungunya virus (CHIKV) | |
2 | A, B, C, D | 6-methyl-2-oxo-2,5-dihydropyrimidine-4-carboxylic acid | non-polymer | 154.1 | 4 | Chemie (TEV) | |||
3 | water | water | 18.0 | 117 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 160 (UniProt: A0A4D6GPC4)
PDB | External Database | Details |
---|---|---|
Gly -7 | - | expression tag |
Ser -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 74075.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 616.5 | |
All* | Total formula weight | 74692.0 |