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6W4C

Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hydroxyacid oxidase 1polymer36840733.91UniProt (Q9UJM8)
Pfam (PF01070)
Homo sapiens (Human)HAOX1,Glycolate oxidase,GOX
2B
(A)
FLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
3C
(A)
5-[[3-[3-(dimethylamino)-1,2,4-oxadiazol-5-yl]-2-oxidanyl-phenyl]methylamino]-2~{H}-indazole-3-carboxylic acidnon-polymer394.41Chemie (SL7)
4D
(A)
waterwater18.0203Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40733.9
Non-Polymers*Number of molecules2
Total formula weight850.7
All*Total formula weight41584.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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