6W41

Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody CR3022

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	CR3022 Fab heavy chain	polymer	222	23455.4	1		Homo sapiens (Human)
2	L	CR3022 Fab light chain	polymer	221	24377.0	1		Homo sapiens (Human)
3	C	Spike protein S1	polymer	231	26095.3	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
4	L	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	L	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6	C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

C: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Ser 542	-	expression tag
Gly 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	73927.7
Non-Polymers*	Number of molecules	4
	Total formula weight	505.4
All*	Total formula weight	74433.2

*Water molecules are not included.