6W3E
Structure of phosphorylated IRE1 in complex with G-0701
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Serine/threonine-protein kinase/endoribonuclease IRE1 | polymer | 431 | 49543.2 | 2 | UniProt (O75460) Pfam (PF00069) Pfam (PF06479) In PDB | Homo sapiens (Human) | Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a |
2 | A, B | methyl ~{N}-[6-methyl-5-[3-[2-[[(3~{S})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate | non-polymer | 484.6 | 2 | Chemie (SJV) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 99086.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 969.1 | |
All* | Total formula weight | 100055.5 |