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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6W2T

Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the closed state (Class 2)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1a18S rRNApolymer1697547733.11Oryctolagus cuniculus
2BuS2polymer29533022.11UniProt (G1TWL4)
Pfam (PF00318)
Pfam (PF16122)
UniProt (by SIFTS) (G1TLT8)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein SA
3CeS1polymer26430002.11UniProt (G1SS70)
Pfam (PF01015)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S3a
4DuS5polymer25527529.21UniProt (G1SWM1)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Oryctolagus cuniculus (Rabbit)S5 DRBM domain-containing protein
5FeS4polymer26329596.81UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S4
6HeS6polymer24928751.91UniProt (G1TM55)
Pfam (PF01092)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S6
7IeS7polymer19422168.91UniProt (G1SVB0)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S7
8JeS8polymer20824263.41UniProt (G1TJW1)
Pfam (PF01201)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S8
9KuS4polymer19422641.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S9
10MuS17polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S11
11OuS15polymer15117259.41UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S13
12PuS11polymer15116302.81UniProt (G1U472)
Pfam (PF00411)
UniProt (by SIFTS) (G1T1F0)
In PDB		Oryctolagus cuniculus (Rabbit)
13WeS21polymer839098.31Oryctolagus cuniculus
14XuS8polymer13014865.61UniProt (G1TG89)
Pfam (PF00410)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S15a
15YuS12polymer14315784.51UniProt (G1SZ47)
Pfam (PF00164)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S23
16ZeS24polymer13415548.41UniProt (G1T3D8)
Pfam (PF01282)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S24
17beS26polymer11513015.51UniProt (G1TFE8)
Pfam (PF01283)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S26
18ceS27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S27
19feS30polymer13314498.91UniProt (G1T8A2)
Pfam (PF00240)
Pfam (PF04758)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S30
20EuS3polymer28131146.61UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S3
21GuS7polymer20422913.51UniProt (G1TFM5)
Pfam (PF00177)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S5
22LeS10polymer14917156.91UniProt (G1TPV3)
Pfam (PF03501)
In PDB		Oryctolagus cuniculus (Rabbit)
23NeS12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S12
24QuS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)
In PDB		Oryctolagus cuniculus (Rabbit)
25RuS9polymer17219213.51UniProt (G1SGX4)
Pfam (PF00380)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S16
26SeS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)
In PDB		Oryctolagus cuniculus (Rabbit)
27TuS13polymer15217759.81UniProt (G1TPG3)
Pfam (PF00416)
In PDB		Oryctolagus cuniculus (Rabbit)
28UeS19polymer14516235.81UniProt (G1TN62)
Pfam (PF01090)
In PDB		Oryctolagus cuniculus (Rabbit)
29VuS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)
In PDB		Oryctolagus cuniculus (Rabbit)
30ieS25polymer12513776.21UniProt (G1TDB3)
Pfam (PF03297)
In PDB		Oryctolagus cuniculus (Rabbit)
31deS28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S28
32eeS29polymer566690.81UniProt (G1U7M4)
Pfam (PF00253)
In PDB		Oryctolagus cuniculus (Rabbit)
33geS31polymer15618004.01UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S27a
34hRACK1polymer31735115.71UniProt (G1SJB4)
Pfam (PF00400)
In PDB		Oryctolagus cuniculus (Rabbit)
353Eukaryotic translation initiation factor 3 subunit Epolymer46254199.91UniProt (G1SUC8)
Pfam (PF09440)
Pfam (PF01399)
Pfam (PF21357)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3e,Eukaryotic translation initiation factor 3 subunit 6,eIF-3 p48
364Eukaryotic translation initiation factor 3 subunit Fpolymer36437846.71UniProt (G1SLC2)
Pfam (PF01398)
Pfam (PF13012)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3f,Eukaryotic translation initiation factor 3 subunit 5,eIF-3-epsilon,eIF3 p47
376Eukaryotic translation initiation factor 3 subunit Kpolymer21825129.71UniProt (G1T3L2)
Pfam (PF10075)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3k,Eukaryotic translation initiation factor 3 subunit 12,eIF-3 p25
387Eukaryotic translation initiation factor 3 subunit Lpolymer60771001.51UniProt (G1SED9)
Pfam (PF10255)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3l,Eukaryotic translation initiation factor 3 subunit 6-interacting protein,Eukaryotic translation initiation factor 3 subunit E-interacting protein
398Eukaryotic translation initiation factor 3 subunit Mpolymer37442555.81UniProt (G1SLW8)
Pfam (PF01399)
Pfam (PF18005)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3m
401Eukaryotic translation initiation factor 3 subunit Apolymer1362164902.71UniProt (G1SMZ5)
Pfam (PF22591)
Pfam (PF01399)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3a,Eukaryotic translation initiation factor 3 subunit 10,eIF-3-theta
412Eukaryotic translation initiation factor 3 subunit Cpolymer913105706.21UniProt (G1U971)
Pfam (PF05470)
Pfam (PF01399)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3c,Eukaryotic translation initiation factor 3 subunit 8,eIF3 p110
429Eukaryotic translation initiation factor 3 subunit Dpolymer55864517.21UniProt (K7IM66)
Pfam (PF05091)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3d,Eukaryotic translation initiation factor 3 subunit 7
435Eukaryotic translation initiation factor 3 subunit Hpolymer36341083.51UniProt (G1ST95)
Pfam (PF01398)
Pfam (PF19445)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3h,Eukaryotic translation initiation factor 3 subunit 3,eIF-3 gamma,eIF3 p40 subunit
44ACrPV 5'-UTR IRESpolymer377121095.01GenBank (8895506)Cricket paralysis virus
45aMAGNESIUM IONnon-polymer24.31Chemie (MG)
46bZINC IONnon-polymer65.41Chemie (ZN)
Sequence modifications
B: 1 - 295 (UniProt: G1TWL4)
PDBExternal DatabaseDetails
Thr 114Ala 114conflict
Thr 135Met 135conflict
Arg 155His 155conflict
Pro 162Leu 162conflict
D: 39 - 293 (UniProt: G1SWM1)
PDBExternal DatabaseDetails
Asn 57Asp 19conflict
Phe 97Cys 59conflict
Pro 181Leu 143conflict
Val 191-insertion
F: 1 - 263 (UniProt: G1TK17)
PDBExternal DatabaseDetails
Gly 25Ser 25conflict
Val 156Met 156conflict
J: 1 - 208 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47conflict
b: 1 - 115 (UniProt: G1TFE8)
PDBExternal DatabaseDetails
Arg 28Cys 28conflict
2: 1 - 913 (UniProt: G1U971)
PDBExternal DatabaseDetails
Glu 671Val 671conflict
A: 357 - 728 (GenBank: 8895506)
PDBExternal DatabaseDetails
U 569C 569conflict
U 570C 570conflict
U 571A 571conflict
U 572C 572conflict
U 574C 574conflict
U 575G 575conflict
G 729-expression tag
G 730-expression tag
A 731-expression tag
U 732-expression tag
C 733-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains44
Total formula weight1904476.3
Non-Polymers*Number of molecules2
Total formula weight89.7
All*Total formula weight1904566.0
*Water molecules are not included.

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PDB entries from 2024-07-24

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