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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6W2S

Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the open state (Class 1)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A18S rRNApolymer1697547733.11Oryctolagus cuniculus
20CrPV 5'-UTR IRESpolymer377121095.01GenBank (8895506)Cricket paralysis virus
3BuS2polymer29533022.11UniProt (G1TWL4)
Pfam (PF00318)
Pfam (PF16122)
UniProt (by SIFTS) (G1TLT8)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein SA
4CeS1polymer26430002.11UniProt (G1SS70)
Pfam (PF01015)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S3a
5DuS5polymer25527529.21UniProt (G1SWM1)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Oryctolagus cuniculus (Rabbit)S5 DRBM domain-containing protein
6FeS4polymer26329596.81UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S4
7HeS6polymer24928751.91UniProt (G1TM55)
Pfam (PF01092)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S6
8IeS7polymer19422168.91UniProt (G1SVB0)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S7
9JeS8polymer20824263.41UniProt (G1TJW1)
Pfam (PF01201)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S8
10KuS4polymer19422641.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S9
11MuS17polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S11
12OuS15polymer15117259.41UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S13
13PuS11polymer15116302.81UniProt (G1U472)
Pfam (PF00411)
UniProt (by SIFTS) (G1T1F0)
In PDB		Oryctolagus cuniculus (Rabbit)
14WeS21polymer839098.31Oryctolagus cuniculus (Rabbit)
15XuS8polymer13014865.61UniProt (G1TG89)
Pfam (PF00410)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S15a
16YuS12polymer14315784.51UniProt (G1SZ47)
Pfam (PF00164)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S23
17ZeS24polymer13415548.41UniProt (G1T3D8)
Pfam (PF01282)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S24
18beS26polymer11513015.51UniProt (G1TFE8)
Pfam (PF01283)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S26
19ceS27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S27
20feS30polymer13314498.91UniProt (G1T8A2)
Pfam (PF00240)
Pfam (PF04758)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S30
21EuS3polymer28131146.61UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S3
22GuS7polymer20422913.51UniProt (G1TFM5)
Pfam (PF00177)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S5
23LeS10polymer14917156.91UniProt (G1TPV3)
Pfam (PF03501)
In PDB		Oryctolagus cuniculus (Rabbit)
24NeS12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)
In PDB		Oryctolagus cuniculus (Rabbit)40S ribosomal protein S12
25QuS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)
In PDB		Oryctolagus cuniculus (Rabbit)
26RuS9polymer17219213.51UniProt (G1SGX4)
Pfam (PF00380)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S16
27SeS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)
In PDB		Oryctolagus cuniculus (Rabbit)
28TuS13polymer15217759.81UniProt (G1TPG3)
Pfam (PF00416)
In PDB		Oryctolagus cuniculus (Rabbit)
29UeS19polymer14516235.81UniProt (G1TN62)
Pfam (PF01090)
In PDB		Oryctolagus cuniculus (Rabbit)
30VuS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)
In PDB		Oryctolagus cuniculus (Rabbit)
31aeS25polymer12513776.21UniProt (G1TDB3)
Pfam (PF03297)
In PDB		Oryctolagus cuniculus (Rabbit)
32deS28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S28
33eeS29polymer566690.81UniProt (G1U7M4)
Pfam (PF00253)
In PDB		Oryctolagus cuniculus (Rabbit)
34geS31polymer15618004.01UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Oryctolagus cuniculus (Rabbit)Ribosomal protein S27a
35hRACK1polymer31735115.71UniProt (G1SJB4)
Pfam (PF00400)
In PDB		Oryctolagus cuniculus (Rabbit)
361Eukaryotic translation initiation factor 3 subunit Apolymer1362164902.71UniProt (G1SMZ5)
Pfam (PF22591)
Pfam (PF01399)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3a,Eukaryotic translation initiation factor 3 subunit 10,eIF-3-theta
372Eukaryotic translation initiation factor 3 subunit Cpolymer913105706.21UniProt (G1U971)
Pfam (PF05470)
Pfam (PF01399)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3c,Eukaryotic translation initiation factor 3 subunit 8,eIF3 p110
383Eukaryotic translation initiation factor 3 subunit Epolymer46254199.91UniProt (G1SUC8)
Pfam (PF09440)
Pfam (PF01399)
Pfam (PF21357)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3e,Eukaryotic translation initiation factor 3 subunit 6,eIF-3 p48
394Eukaryotic translation initiation factor 3 subunit Fpolymer36437846.71UniProt (G1SLC2)
Pfam (PF01398)
Pfam (PF13012)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3f,Eukaryotic translation initiation factor 3 subunit 5,eIF-3-epsilon,eIF3 p47
405Eukaryotic translation initiation factor 3 subunit Hpolymer36341083.51UniProt (G1ST95)
Pfam (PF01398)
Pfam (PF19445)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3h,Eukaryotic translation initiation factor 3 subunit 3,eIF-3 gamma,eIF3 p40 subunit
416Eukaryotic translation initiation factor 3 subunit Kpolymer21825129.71UniProt (G1T3L2)
Pfam (PF10075)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3k,Eukaryotic translation initiation factor 3 subunit 12,eIF-3 p25
427Eukaryotic translation initiation factor 3 subunit Lpolymer60771001.51UniProt (G1SED9)
Pfam (PF10255)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3l,Eukaryotic translation initiation factor 3 subunit 6-interacting protein,Eukaryotic translation initiation factor 3 subunit E-interacting protein
438Eukaryotic translation initiation factor 3 subunit Mpolymer37442555.81UniProt (G1SLW8)
Pfam (PF01399)
Pfam (PF18005)
In PDB		Oryctolagus cuniculus (Rabbit)eIF3m
44AMAGNESIUM IONnon-polymer24.31Chemie (MG)
45bZINC IONnon-polymer65.41Chemie (ZN)
Sequence modifications
0: 357 - 728 (GenBank: 8895506)
PDBExternal DatabaseDetails
U 569C 569conflict
U 570C 570conflict
U 571A 571conflict
U 572C 572conflict
U 574C 574conflict
U 575G 575conflict
G 729-expression tag
G 730-expression tag
A 731-expression tag
U 732-expression tag
C 733-expression tag
B: 1 - 295 (UniProt: G1TWL4)
PDBExternal DatabaseDetails
Thr 114Ala 114conflict
Thr 135Met 135conflict
Arg 155His 155conflict
Pro 162Leu 162conflict
D: 39 - 293 (UniProt: G1SWM1)
PDBExternal DatabaseDetails
Asn 57Asp 19conflict
Phe 97Cys 59conflict
Pro 181Leu 143conflict
Val 191-insertion
F: 1 - 263 (UniProt: G1TK17)
PDBExternal DatabaseDetails
Gly 25Ser 25conflict
Val 156Met 156conflict
J: 1 - 208 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47conflict
b: 1 - 115 (UniProt: G1TFE8)
PDBExternal DatabaseDetails
Arg 28Cys 28conflict
2: 1 - 913 (UniProt: G1U971)
PDBExternal DatabaseDetails
Glu 671Val 671conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains43
Total formula weight1839959.1
Non-Polymers*Number of molecules2
Total formula weight89.7
All*Total formula weight1840048.8
*Water molecules are not included.

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PDB entries from 2024-07-24

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