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6W12

Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to the Tumor-Associated Tn Antigen

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
C-type lectin domain family 10 member Apolymer12914842.21UniProt (Q8IUN9)
Pfam (PF00059)
Homo sapiens (Human)C-type lectin superfamily member 14,Macrophage lectin 2
2B, C, D, E, F...
(A)
CALCIUM IONnon-polymer40.16Chemie (CA)
3H, I, J, K, L
(A)
CHLORIDE IONnon-polymer35.55Chemie (CL)
4M
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5N
(A)
SERINEnon-polymer105.11Chemie (SER)
6O
(A)
2-acetamido-2-deoxy-alpha-D-galactopyranosenon-polymer221.21Chemie (A2G)
7P
(A)
waterwater18.0104Chemie (HOH)
Sequence modifications
A: 181 - 308 (UniProt: Q8IUN9)
PDBExternal DatabaseDetails
Ser 180-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight14842.2
Non-Polymers*Number of molecules14
Total formula weight809.4
All*Total formula weight15651.6
*Water molecules are not included.

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PDB entries from 2025-10-15

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