6VXI
Structure of ABCG2 bound to mitoxantrone
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Broad substrate specificity ATP-binding cassette transporter ABCG2 | polymer | 655 | 72385.9 | 2 | UniProt (Q9UNQ0) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) In PDB | Homo sapiens (Human) | ATP-binding cassette sub-family G member 2,Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter |
2 | A, B | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) | |||
3 | B | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE | non-polymer | 444.5 | 1 | Chemie (MIX) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 144771.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1217.8 | |
All* | Total formula weight | 145989.5 |