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6VXI

Structure of ABCG2 bound to mitoxantrone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BBroad substrate specificity ATP-binding cassette transporter ABCG2polymer65572385.92UniProt (Q9UNQ0)
Pfam (PF00005)
Pfam (PF19055)
Pfam (PF01061)
In PDB
Homo sapiens (Human)ATP-binding cassette sub-family G member 2,Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter
2A, BCHOLESTEROLnon-polymer386.72Chemie (CLR)
3B1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONEnon-polymer444.51Chemie (MIX)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight144771.7
Non-Polymers*Number of molecules3
Total formula weight1217.8
All*Total formula weight145989.5
*Water molecules are not included.

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PDB entries from 2024-05-01

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