6VXC

Crystal structure of hydroxyproline dehydratase (HypD) from Clostridioides difficile

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Trans-4-hydroxy-L-proline dehydratase	polymer	809	91456.6	8	UniProt (A0A031WDE4) Pfam (PF02901) Pfam (PF01228) UniProt (by SIFTS) (Q180C6) In PDB	Clostridioides difficile 70-100-2010	Glycyl radical enzyme,Hyp dehydratase,HypD
2	A, B, C, D, E...	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
3		water	water		18.0	4815	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 789 (UniProt: A0A031WDE4)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	731652.9
Non-Polymers*	Number of molecules	8
	Total formula weight	736.8
All*	Total formula weight	732389.6

*Water molecules are not included.