6VVS
Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with antibiotic Sorangicin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, K (A, B, T) | DNA-directed RNA polymerase subunit alpha | polymer | 350 | 37959.4 | 3 | UniProt (A0QSL8) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C (C) | DNA-directed RNA polymerase subunit beta | polymer | 1169 | 128680.1 | 1 | UniProt (P60281) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D (D) | DNA-directed RNA polymerase subunit beta' | polymer | 1317 | 146712.9 | 1 | UniProt (A0QS66) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E (E) | DNA-directed RNA polymerase subunit omega | polymer | 107 | 11544.8 | 1 | UniProt (A0QWT1) Pfam (PF01192) | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
| 5 | F (F) | RNA polymerase sigma factor SigA | polymer | 466 | 51573.6 | 1 | UniProt (A0QW02) Pfam (PF00140) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | |
| 6 | G (G) | unknown | polymer | 17 | 1464.8 | 1 | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | ||
| 7 | H (J) | RNA polymerase-binding protein RbpA | polymer | 114 | 13078.7 | 1 | UniProt (A0QZ11) Pfam (PF13397) | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | |
| 8 | I (O) | DNA (31-MER) | polymer | 31 | 9565.2 | 1 | synthetic construct | ||
| 9 | J (P) | DNA (26-MER) | polymer | 26 | 7930.2 | 1 | synthetic construct | ||
| 10 | BA, DA, EA, FA, GA... (D, F, C) | SULFATE ION | non-polymer | 96.1 | 14 | Chemie (SO4) | |||
| 11 | AA, CA, IA, O, R... (D, F, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 12 | P (C) | SORANGICIN A | non-polymer | 807.0 | 1 | Chemie (SRN) PubChem (163697) PubChem (71155416) PubChem (10056177) PubChem (14263066) PubChem (23305250) PubChem (24893440) PubChem (44249558) PubChem (177507279) PubChem (24893439) PubChem (50919084) PubChem (176538828) PubChem (177459535) PubChem (14263065) PubChem (657059) PubChem (6441166) PubChem (124015068) PubChem (10010602) PubChem (10395584) PubChem (134942430) PubChem (135023736) PubChem (137171788) PubChem (139583235) PubChem (158950178) PubChem (161086790) PubChem (162854734) PubChem (162854739) PubChem (163319902) PubChem (172784789) PubChem (177726415) PubChem (90294669) PubChem (135024311) PubChem (158086067) PubChem (162854735) PubChem (162854736) PubChem (162854737) PubChem (162854738) PubChem (162854740) PubChem (162854741) PubChem (162854742) PubChem (162854743) PubChem (163319900) PubChem (163319901) | |||
| 13 | S, T (D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 14 | JA, KA, LA, MA, NA... (C, D, E, F, J...) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 484428.5 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2717.2 | |
| All* | Total formula weight | 487145.7 |
