6VVB
Mycobacterium tuberculosis dihydrofolate reductase in complex with 6-methyl-5-(4-phenylthiazol-2-yl)-2- (trifluoromethyl)nicotinic acid (fragment 10)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydrofolate reductase | polymer | 161 | 17893.3 | 1 | UniProt (P9WNX1) Pfam (PF00186) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | A | 6-methyl-5-(4-phenyl-1,3-thiazol-2-yl)-2-(trifluoromethyl)pyridine-3-carboxylic acid | non-polymer | 364.3 | 1 | Chemie (RQ4) | |||
| 3 | A | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 1 | Chemie (P33) | |||
| 4 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 5 | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17893.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1434.1 | |
| All* | Total formula weight | 19327.4 |
