6VU8

Structure of G-alpha-i bound to its chaperone Ric-8A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)	polymer	534	60512.1	1	UniProt (B1H241) Pfam (PF10165) UniProt (by SIFTS) (Q80ZG1)	Rattus norvegicus (Rat)	Ric8a protein,Synembryn-A
2	B (B)	Guanine nucleotide-binding protein G(i) subunit alpha-1	polymer	359	41112.7	1	UniProt (P63096) Pfam (PF00503)	Homo sapiens (Human)	Adenylate cyclase-inhibiting G alpha protein

Sequence modifications

A: 1 - 530 (UniProt: B1H241)

PDB	External Database	Details
Gln -3	-	expression tag
Gly -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag
Phe 232	Tyr 232	engineered mutation

B: 2 - 354 (UniProt: P63096)

PDB	External Database	Details
His 56	-	insertion
His 56	-	insertion
His 56	-	insertion
His 56	-	insertion
His 56	-	insertion
His 56	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	101624.8
All*	Total formula weight	101624.8

*Water molecules are not included.