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6VTX

Crystal structure of human KLF4 zinc finger DNA binding domain in complex with NANOG DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Krueppel-like factor 4polymer849998.31UniProt (O43474)
Pfam (PF00096)
Homo sapiens (Human)Epithelial zinc finger protein EZF,Gut-enriched krueppel-like factor
2B
(B)
DNA (5'-D(*AP*GP*GP*GP*GP*GP*TP*GP*TP*GP*CP*C)-3')polymer123759.41Homo sapiens
3C
(C)
DNA (5'-D(*GP*GP*CP*AP*CP*AP*CP*CP*CP*CP*CP*T)-3')polymer123568.31Homo sapiens
4D, E, F
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
5G
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
6H, I, J
(A, B, C)
waterwater18.081Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight17326.1
Non-Polymers*Number of molecules4
Total formula weight219.2
All*Total formula weight17545.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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