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6VSG

Mycobacterium tuberculosis dihydrofolate reductase in complex with 4-(trifluoromethyl)benzene-1,2-diamine(fragment 17)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Dihydrofolate reductasepolymer16117893.32UniProt (P9WNX1)
Pfam (PF00186)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2C, D
(A)
COBALT (II) IONnon-polymer58.92Chemie (CO)
3E
(A)
4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINEnon-polymer176.11Chemie (X0V)
4F
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5G, H
(A, B)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.42Chemie (NAP)
6I, J
(A, B)
waterwater18.0200Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35786.6
Non-Polymers*Number of molecules6
Total formula weight1872.9
All*Total formula weight37659.5
*Water molecules are not included.

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PDB entries from 2025-07-16

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