6VSG
Mycobacterium tuberculosis dihydrofolate reductase in complex with 4-(trifluoromethyl)benzene-1,2-diamine(fragment 17)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase | polymer | 161 | 17893.3 | 2 | UniProt (P9WNX1) Pfam (PF00186) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | C, D (A) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) PubChem (104729) | |||
| 3 | E (A) | 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE | non-polymer | 176.1 | 1 | Chemie (X0V) PubChem (520822) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | G, H (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35786.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1872.9 | |
| All* | Total formula weight | 37659.5 |
