6VSF
Mycobacterium tuberculosis dihydrofolate reductase in complex with 4-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-4-oxobutanoic acid(fragment 16)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase | polymer | 161 | 17893.3 | 2 | UniProt (P9WNX1) Pfam (PF00186) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | C, H, I (A, B) | 4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-oxobutanoic acid | non-polymer | 250.2 | 3 | Chemie (RKY) PubChem (2775652) | |||
| 3 | D, J (A, B) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) PubChem (104729) | |||
| 4 | E, K (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010) | |||
| 5 | F, L (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 6 | G, M, N (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) PubChem (1061) | |||
| 7 | O, P (A, B) | water | water | 18.0 | 293 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35786.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2824.5 | |
| All* | Total formula weight | 38611.1 |
