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6VSE

Mycobacterium tuberculosis dihydrofolate reductase in complex with 3-(phenoxymethyl)benzoic acid(fragment 14)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Dihydrofolate reductasepolymer16117893.32UniProt (P9WNX1)
Pfam (PF00186)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2C, E
(A, B)
COBALT (II) IONnon-polymer58.92Chemie (CO)
3D, F
(A, B)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.42Chemie (NAP)
4G
(B)
3-(phenoxymethyl)benzoic acidnon-polymer228.21Chemie (4RG)
5H
(B)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
6I, J
(A, B)
waterwater18.0182Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35786.6
Non-Polymers*Number of molecules6
Total formula weight1927.9
All*Total formula weight37714.5
*Water molecules are not included.

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PDB entries from 2024-11-06

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