6VS5
Mycobacterium tuberculosis dihydrofolate reductase in complex with 5-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid (fragment 1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Dihydrofolate reductase | polymer | 161 | 17893.3 | 2 | UniProt (A0A0E8UVJ4) Pfam (PF00186) UniProt (by SIFTS) (P9WNX1) In PDB | Mycobacterium tuberculosis | |
| 2 | A, B | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 3 | A, B | 5-methyl-1-phenyl-pyrazole-4-carboxylic acid | non-polymer | 202.2 | 4 | Chemie (9FH) | |||
| 4 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 5 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 6 | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35786.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2702.5 | |
| All* | Total formula weight | 38489.0 |
