6VRR
Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium channel subunit beta-2 | polymer | 127 | 14768.7 | 1 | UniProt (O60939) Pfam (PF07686) | Homo sapiens (Human) | |
| 2 | B, C (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | D (A) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A: 30 - 153 (UniProt: O60939)
| PDB | External Database | Details |
|---|---|---|
| Ser 27 | - | expression tag |
| Asn 28 | - | expression tag |
| Ala 29 | - | expression tag |
| Ala 55 | Cys 55 | conflict |
| His 137 | Arg 137 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14768.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 14952.8 |
