6VQS
HIV Integrase Core domain (IN) in complex with [5-(3-fluorophenyl)-1-benzofuran-3-yl]acetic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrase | polymer | 163 | 17841.3 | 1 | UniProt (Q76353) Pfam (PF00665) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | B, C, D (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E, F, G, H (A) | IODIDE ION | non-polymer | 126.9 | 4 | Chemie (IOD) | |||
| 4 | I (A) | [5-(3-fluorophenyl)-1-benzofuran-3-yl]acetic acid | non-polymer | 270.3 | 1 | Chemie (R7J) | |||
| 5 | J (A) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 50 - 212 (UniProt: Q76353)
| PDB | External Database | Details |
|---|---|---|
| Glu 53 | Gln 53 | conflict |
| Ser 56 | Cys 56 | conflict |
| Glu 131 | Trp 131 | conflict |
| Lys 185 | Phe 185 | conflict |
| Glu 209 | Gln 209 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17841.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1066.1 | |
| All* | Total formula weight | 18907.3 |
