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6VQM

Crystal Structure Analysis of human ACK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BActivated CDC42 kinase 1polymer28932781.82UniProt (Q07912)
Pfam (PF07714)
In PDB
Homo sapiens (Human)ACK-1,Tyrosine kinase non-receptor protein 2
2A, B2-({4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl}amino)-9-methyl-5,7-dihydro-6H-pyrimido[5,4-d][1,3]benzodiazepin-6-onenon-polymer459.52Chemie (R7P)
3BSULFATE IONnon-polymer96.11Chemie (SO4)
Sequence modifications
A, B: 109 - 395 (UniProt: Q07912)
PDBExternal DatabaseDetails
Gly 107-expression tag
Ser 108-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight65563.5
Non-Polymers*Number of molecules3
Total formula weight1015.1
All*Total formula weight66578.7
*Water molecules are not included.

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PDB entries from 2024-07-24

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