6VQM
Crystal Structure Analysis of human ACK1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Activated CDC42 kinase 1 | polymer | 289 | 32781.8 | 2 | UniProt (Q07912) Pfam (PF07714) | Homo sapiens (Human) | ACK-1,Tyrosine kinase non-receptor protein 2 |
| 2 | C, D (A, B) | 2-({4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-2-methoxyphenyl}amino)-9-methyl-5,7-dihydro-6H-pyrimido[5,4-d][1,3]benzodiazepin-6-one | non-polymer | 459.5 | 2 | Chemie (R7P) | |||
| 3 | E (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) |
Sequence modifications
A, B: 109 - 395 (UniProt: Q07912)
| PDB | External Database | Details |
|---|---|---|
| Gly 107 | - | expression tag |
| Ser 108 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65563.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1015.1 | |
| All* | Total formula weight | 66578.7 |
