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6VPX

Nanodisc of full-length HIV-1 Envelope glycoprotein clone AMC011 in complex with one PGT151 Fab and three 10E8 Fabs

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, E, C)
Envelope glycoprotein gp120polymer46551997.13Pfam (PF00516)
UniProt (by SIFTS) (B9V6B3)
Human immunodeficiency virus 1
2D, E, F
(D, B, F)
Envelope glycoprotein gp41polymer15317298.63Pfam (PF00517)
UniProt (by SIFTS) (B0FAM5)
Human immunodeficiency virus 1
3G, J, M
(H, K, M)
Antibody 10E8 Fab heavy chainpolymer12914433.13Homo sapiens (Human)
4H, K, N
(L, N, O)
Antibody 10E8 Fab light chainpolymer10811585.83Homo sapiens (Human)
5I, L, O
(G, I, J)
MPER peptidepolymer172147.53UniProt (by SIFTS) (P05880)Homo sapiens (Human)
6P
(P)
Antibody PGT151 Fab heavy chainpolymer13415090.01Homo sapiens (Human)
7Q
(Q)
Antibody PGT151 Fab light chainpolymer10911940.41Homo sapiens (Human)
8AA, BA, DA, EA, FA...
(a, b, d, e, f...)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.412In PDB
GlyTouCan (G42666HT)
9S
(S)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G35932AR)
10W
(W)
alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G81315DD)
11CA, Y
(c, Y)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.52In PDB
GlyTouCan (G15407YE)
12GA
(g)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G22768VO)
13HA, NA
(h, n)
alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched367.32In PDB
GlyTouCan (G86851RC)
14JA, KA
(j, k)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched570.52In PDB
GlyTouCan (G21290RB)
15LA
(l)
beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched1625.51In PDB
GlyTouCan (G42672MA)
16MA
(m)
beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched1422.31In PDB
GlyTouCan (G04744XB)
17AB, AC, BB, BC, CB...
(E, D, F, C, A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.243Chemie (NAG)
18FC, GC, HC
(L, N, O)
(2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoatenon-polymer368.43Chemie (44E)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains17
Total formula weight319416.7
BranchedNumber of molecules23
Total formula weight13273.4
Non-Polymers*Number of molecules46
Total formula weight10617.0
All*Total formula weight343307.1
*Water molecules are not included.

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PDB entries from 2024-11-20

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