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6VP6

Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Leucine-rich repeat serine/threonine-protein kinase 2polymer1201136943.63UniProt (Q5S007)
Pfam (PF08477)
Pfam (PF16095)
Pfam (PF00069)
Homo sapiens (Human)Dardarin
2D
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight410830.8
Non-Polymers*Number of molecules2
Total formula weight467.5
All*Total formula weight411298.3
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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