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6VP6

Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Leucine-rich repeat serine/threonine-protein kinase 2polymer1201136943.63UniProt (Q5S007)
Pfam (PF08477)
Pfam (PF16095)
Pfam (PF25497)
Pfam (PF00069)
Pfam (PF23748)
Homo sapiens (Human)Dardarin
2D
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
3E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight410830.8
Non-Polymers*Number of molecules2
Total formula weight467.5
All*Total formula weight411298.3
*Water molecules are not included.

251801

PDB entries from 2026-04-08

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