6VO1
BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20J
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, C, D) | Envelope glycoprotein gp120 | polymer | 475 | 53268.4 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 (HIV-1) | BG505 SOSIP.v5.2 gp120 |
| 2 | B, F, J (B, E, F) | Envelope glycoprotein gp41 | polymer | 153 | 17178.5 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 (HIV-1) | BG505 SOSIP.v5.2 gp41 |
| 3 | C, G, K (H, G, I) | RM20J Heavy chain Fab | polymer | 118 | 12714.1 | 3 | Macaca mulatta (Rhesus monkey) | ||
| 4 | D, H, L (L, J, K) | RM20J Kappa light chain | polymer | 107 | 11552.8 | 3 | Macaca mulatta (Rhesus monkey) | ||
| 5 | AA, BA, CA, DA, EA... (a, b, c, d, e...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 21 | In PDB GlyTouCan (G42666HT) | |||
| 6 | FA, N, W (f, N, W) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 7 | IA, Q, Z (i, Q, Z) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G56014GC) | |||
| 8 | AB, BB, CB, DB, EB... (D, A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 18 | Chemie (NAG) |
Sequence modifications
A, C, D: 31 - 507 (UniProt: Q2N0S6)
B, E, F: 512 - 664 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Lys 64 | Glu 63 | conflict |
| Cys 73 | Ala 72 | conflict |
| Trp 316 | Ala 313 | conflict |
| Asn 332 | Thr 330 | conflict |
| Cys 501 | Ala 498 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 556 | conflict |
| Cys 561 | Ala 558 | conflict |
| Cys 605 | Thr 602 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 284141.4 | |
| Branched | Number of molecules | 27 |
| Total formula weight | 13890.9 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3981.7 | |
| All* | Total formula weight | 302014.0 |
