6VLG

Crystal structure of mouse alpha 1,6-fucosyltransferase, FUT8 bound to GDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Alpha-(1,6)-fucosyltransferase	polymer	543	62603.8	4	UniProt (Q9WTS2) Pfam (PF19745) Pfam (PF14604) In PDB	Mus musculus (Mouse)	Alpha1-6FucT,Fucosyltransferase 8,GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase,GDP-fucose--glycoprotein fucosyltransferase,Glycoprotein 6-alpha-L-fucosyltransferase
2	A, B, C, D	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	4	Chemie (GDP)
3	A, B, C, D	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4	C	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
5	D	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
6		water	water		18.0	925	Chemie (HOH)

Sequence modifications

A, B, C, D: 68 - 575 (UniProt: Q9WTS2)

PDB	External Database	Details
Ala 33	-	expression tag
Asp 34	-	expression tag
Leu 35	-	expression tag
Gly 36	-	expression tag
Ser 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
His 40	-	expression tag
His 41	-	expression tag
His 42	-	expression tag
His 43	-	expression tag
His 44	-	expression tag
His 45	-	expression tag
His 46	-	expression tag
His 47	-	expression tag
Gly 48	-	expression tag
Lys 49	-	expression tag
Pro 50	-	expression tag
Ile 51	-	expression tag
Pro 52	-	expression tag
Asn 53	-	expression tag
Pro 54	-	expression tag
Leu 55	-	expression tag
Leu 56	-	expression tag
Gly 57	-	expression tag
Leu 58	-	expression tag
Asp 59	-	expression tag
Ser 60	-	expression tag
Thr 61	-	expression tag
Ile 62	-	expression tag
Asp 63	-	expression tag
Gly 64	-	expression tag
Arg 65	-	expression tag
Glu 66	-	expression tag
Phe 67	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	250415.1
Non-Polymers*	Number of molecules	10
	Total formula weight	2501.5
All*	Total formula weight	252916.6

*Water molecules are not included.