6VKN
BG505 SOSIP.v5.2.N241.N289 in complex with rhesus macaque Fab RM19R
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D | Envelope glycoprotein gp160 | polymer | 475 | 53265.3 | 3 | UniProt (Q2N0S6) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 (HIV-1) | Env polyprotein |
| 2 | B, E, F | BG505 SOSIPv5.2 gp41 | polymer | 153 | 17178.5 | 3 | UniProt (Q2N0S6) Pfam (PF00517) In PDB | Human immunodeficiency virus 1 (HIV-1) | Env polyprotein |
| 3 | L, J, K | RM19R Kappa Light Chain | polymer | 107 | 11808.1 | 3 | Macaca mulatta | ||
| 4 | H, G, I | RM19R Heavy Chain | polymer | 121 | 13268.7 | 3 | Macaca mulatta | ||
| 5 | b, c, d, e, f... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 18 | In PDB GlyTouCan (G42666HT) | |||
| 6 | g, Q, Y | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G56014GC) | |||
| 7 | a, i, S | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 8 | C, E, A, D, B... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 39 | Chemie (NAG) |
Sequence modifications
A, C, D: 31 - 507 (UniProt: Q2N0S6)
B, E, F: 512 - 664 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Lys 64 | Glu 63 | engineered mutation |
| Cys 73 | Ala 72 | engineered mutation |
| Thr 240 | Pro 239 | engineered mutation |
| Asn 241 | Ser 240 | engineered mutation |
| Ile 271 | Met 270 | engineered mutation |
| Leu 288 | Phe 287 | engineered mutation |
| Glu 290 | Thr 289 | engineered mutation |
| Ser 291 | Pro 290 | engineered mutation |
| Trp 316 | Ala 313 | engineered mutation |
| Asn 332 | Thr 330 | engineered mutation |
| Cys 501 | Ala 498 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 556 | engineered mutation |
| Cys 561 | Ala 558 | engineered mutation |
| Cys 605 | Thr 602 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 286562.0 | |
| Branched | Number of molecules | 24 |
| Total formula weight | 12569.7 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 8627.1 | |
| All* | Total formula weight | 307758.8 |
