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6VJZ

CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
Degradation in the endoplasmic reticulum protein 1polymer21124411.71UniProt (P38307)
Pfam (PF04511)
Saccharomyces cerevisiae (Baker's yeast)
2B
(B)
ERAD-associated E3 ubiquitin-protein ligase HRD1polymer48055638.81UniProt (Q08109)
Pfam (PF25563)
Pfam (PF13639)
Saccharomyces cerevisiae (Baker's yeast)HMG-CoA reductase degradation protein 1,RING-type E3 ubiquitin transferase HRD1
3C
(A)
ERAD-associated E3 ubiquitin-protein ligase component HRD3polymer76788239.11UniProt (Q05787)
Pfam (PF08238)
Saccharomyces cerevisiae (Baker's yeast)HMG-CoA reductase degradation protein 3
4D
(D)
U1 SNP1-associating protein 1polymer33939944.31UniProt (Q03714)Saccharomyces cerevisiae (Baker's yeast)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight208233.9
All*Total formula weight208233.9
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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