6VJC
LmFPPS mutant T164Y in complex with 476A, IPP & Ca
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Farnesyl pyrophosphate synthase | polymer | 362 | 41107.3 | 2 | UniProt (Q4QBL1) Pfam (PF00348) In PDB | Leishmania major | |
2 | A, B | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
3 | A, B | ISOPENTYL PYROPHOSPHATE | non-polymer | 248.1 | 2 | Chemie (IPR) | |||
4 | A, B | 3-butyl-1-(2,2-diphosphonoethyl)pyridinium | non-polymer | 324.2 | 2 | Chemie (476) | |||
5 | A, B | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
6 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
7 | water | water | 18.0 | 698 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 362 (UniProt: Q4QBL1)
PDB | External Database | Details |
---|---|---|
Fme 1 | - | expression tag |
Tyr 164 | Thr 164 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 82214.5 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 1609.3 | |
All* | Total formula weight | 83823.9 |