6VJ5
Structure of PE25-PPE41(A124L) in complex with EspG5 chaperone from the type VII (ESX-5) secretion system
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PE-PGRS family protein PE25 | polymer | 101 | 10894.3 | 1 | UniProt (I6X486) Pfam (PF00934) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | B (B) | PPE family protein PPE41 | polymer | 194 | 22005.8 | 1 | UniProt (Q79FE1) Pfam (PF00823) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 3 | C (C) | ESX-5 secretion-associated protein EspG5 | polymer | 300 | 32384.3 | 1 | UniProt (B2HSU5) Pfam (PF14011) | Mycobacterium marinum (strain ATCC BAA-535 / M) | |
| 4 | D, E (B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | F, G, H (A, B, C) | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A: 1 - 99 (UniProt: I6X486)
B: 1 - 194 (UniProt: Q79FE1)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 124 | Ala 124 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 65284.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 65355.4 |
