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6VJ3

Carbonic Anhydrase II in complex with pyrimidine-based inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer25829070.81UniProt (P00918)
Pfam (PF00194)
Homo sapiens (Human)Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-N-(4-sulfamoylphenyl)acetamidenon-polymer324.31Chemie (QYA)
4D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5E
(A)
waterwater18.0245Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29070.8
Non-Polymers*Number of molecules3
Total formula weight481.8
All*Total formula weight29552.6
*Water molecules are not included.

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PDB entries from 2026-01-14

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