6VHH

Human Teneurin-2 and human Latrophilin-3 binary complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Teneurin-2	polymer	1928	216254.6	1	UniProt (Q9NT68) Pfam (PF15636) In PDB	Homo sapiens (Human)	Ten-2,Protein Odd Oz/ten-m homolog 2,Tenascin-M2,Ten-m2,Teneurin transmembrane protein 2
2	B	Adhesion G protein-coupled receptor L3	polymer	852	95209.6	1	UniProt (Q9HAR2) Pfam (PF02140) Pfam (PF02191) Pfam (PF02793) Pfam (PF16489) Pfam (PF01825) In PDB	Homo sapiens (Human)	Calcium-independent alpha-latrotoxin receptor 3,CIRL-3,Latrophilin-3,Lectomedin-3
3	C	alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G62182OO)
4	D	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	E, F, G	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
6	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A: 727 - 2648 (UniProt: Q9NT68)

PDB	External Database	Details
Ser 1728	Asn 1717	conflict
Gly 2345	Asp 2334	conflict
Lys 2403	Thr 2392	conflict
His 2649	-	expression tag
His 2650	-	expression tag
His 2651	-	expression tag
His 2652	-	expression tag
His 2653	-	expression tag
His 2654	-	expression tag

B: 21 - 866 (UniProt: Q9HAR2)

PDB	External Database	Details
His 867	-	expression tag
His 868	-	expression tag
His 869	-	expression tag
His 870	-	expression tag
His 871	-	expression tag
His 872	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	311464.2
Branched	Number of molecules	5
	Total formula weight	2446.3
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	314574.1

*Water molecules are not included.