6VFR

Crystal structure of human protocadherin 18 EC1-EC4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protocadherin-18	polymer	436	48968.7	2	UniProt (Q9HCL0) Pfam (PF08266) Pfam (PF00028) In PDB	Homo sapiens (Human)
2	C	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
3	D	alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G80587NA)
4	E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
5	F	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	1	In PDB GlyTouCan (G82348BZ)
6	B, A	CALCIUM ION	non-polymer		40.1	18	Chemie (CA)
7	B, A	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
8	B, A	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
9	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
10		water	water		18.0	44	Chemie (HOH)

Sequence modifications

A, B: 1 - 430 (UniProt: Q9HCL0)

PDB	External Database	Details
His 431	-	expression tag
His 432	-	expression tag
His 433	-	expression tag
His 434	-	expression tag
His 435	-	expression tag
His 436	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97937.4
Branched	Number of molecules	4
	Total formula weight	2727.5
Non-Polymers*	Number of molecules	30
	Total formula weight	1706.3
All*	Total formula weight	102371.2

*Water molecules are not included.