6VET

Human insulin analog: [GluB10,HisA8,ArgA9,TyrB20]-DOI

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Insulin A chain	polymer	21	2490.9	3	UniProt (P01308)	Homo sapiens
2	B, D, F (B, D, F)	Insulin B chain	polymer	22	2588.0	3	UniProt (P01308)	Homo sapiens
3	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	119	Chemie (HOH)

Sequence modifications

A, C, E: 1 - 21 (UniProt: P01308)

PDB	External Database	Details
His 8	Thr 97	engineered mutation
Arg 9	Ser 98	engineered mutation

B, D, F: 1 - 22 (UniProt: P01308)

PDB	External Database	Details
Glu 10	His 34	engineered mutation
Tyr 20	Gly 44	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	15236.5
All*	Total formula weight	15236.5

*Water molecules are not included.