6VEB

Precorrin-2-bound S128A S. typhimurium siroheme synthase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Siroheme synthase	polymer	457	50190.5	2	UniProt (A0A3U8X2F7) Pfam (PF13241) Pfam (PF14824) Pfam (PF10414) Pfam (PF00590) UniProt (by SIFTS) (P25924)	Salmonella enterica I
2	C, J (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
3	D (A)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	1	Chemie (NAD)
4	E, F, G, H, I... (A, B)	CHLORIDE ION	non-polymer		35.5	7	Chemie (CL) PubChem (312)
5	K (B)	3,3',3'',3'''-[(7S,8S,12S,13S)-3,8,13,17-tetrakis(carboxymethyl)-8,13-dimethyl-7,8,12,13,20,24-hexahydroporphyrin-2,7,1 2,18-tetrayl]tetrapropanoic acid	non-polymer		864.8	1	Chemie (PQ2)
6	N, O (A, B)	water	water		18.0	207	Chemie (HOH)

Sequence modifications

A, B: 1 - 457 (UniProt: A0A3U8X2F7)

PDB	External Database	Details
Ala 128	Ser 128	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	100381.0
Non-Polymers*	Number of molecules	11
	Total formula weight	2545.3
All*	Total formula weight	102926.3

*Water molecules are not included.