6VCV
Aspergillus fumigatus FKBP12 protein bound with APX879 in P1 space group
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | FK506-binding protein 1A | polymer | 115 | 12426.0 | 2 | UniProt (Q4WLV6) Pfam (PF00254) In PDB | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) | FKBP,Peptidyl-prolyl cis-trans isomerase,PPIase,Rapamycin-binding protein |
2 | A, B | N'-[(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-1,20,21-trioxo-8-(prop-2-en-1-yl)-1,3,4,5,6,8,11,12,13,14,15,16,17,18,19,20,21,23,24,25,26,26a-docosahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosin-7-ylidene]acetohydrazide | non-polymer | 860.1 | 2 | Chemie (R27) | |||
3 | water | water | 18.0 | 332 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 112 (UniProt: Q4WLV6)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 24852.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1720.2 | |
All* | Total formula weight | 26572.1 |