6VCU
Homo sapiens FKBP12 protein bound with APX879 in P32 space group
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Peptidyl-prolyl cis-trans isomerase FKBP1A | polymer | 111 | 12250.0 | 4 | UniProt (P62942) Pfam (PF00254) In PDB | Homo sapiens (Human) | PPIase FKBP1A,12 kDa FK506-binding protein,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase |
| 2 | A, B, D | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 3 | A, B, C, D | N'-[(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-1,20,21-trioxo-8-(prop-2-en-1-yl)-1,3,4,5,6,8,11,12,13,14,15,16,17,18,19,20,21,23,24,25,26,26a-docosahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosin-7-ylidene]acetohydrazide | non-polymer | 860.1 | 4 | Chemie (R27) | |||
| 4 | water | water | 18.0 | 591 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 0 - 107 (UniProt: P62942)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 48999.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 3735.6 | |
| All* | Total formula weight | 52735.5 |
