6VBE
Crystal structure of recombinant mutant H180R of human fumarase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fumarate hydratase, mitochondrial | polymer | 466 | 50158.4 | 2 | UniProt (P07954) Pfam (PF00206) Pfam (PF10415) | Homo sapiens (Human) | HsFH |
| 2 | C, D, E (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | F (B) | L(+)-TARTARIC ACID | non-polymer | 150.1 | 1 | Chemie (TLA) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 579 | Chemie (HOH) |
Sequence modifications
A, B: 45 - 510 (UniProt: P07954)
| PDB | External Database | Details |
|---|---|---|
| Arg 180 | His 180 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100316.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 426.4 | |
| All* | Total formula weight | 100743.3 |
