6VAA

Structure of the Fanconi Anemia ID complex bound to ICL DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Fanconi anemia, complementation group I	polymer	1328	149566.0	1	UniProt (B7ZMF2) Pfam (PF14674) Pfam (PF14675) Pfam (PF14679) Pfam (PF14676) Pfam (PF14680) Pfam (PF14677) Pfam (PF14678) UniProt (by SIFTS) (Q9NVI1)	Homo sapiens (Human)
2	B (B)	Fanconi anemia group D2 protein	polymer	1451	164314.5	1	UniProt (Q9BXW9) Pfam (PF14631)	Homo sapiens (Human)	Protein FACD2
3	C (W)	DNA (26-MER)	polymer	27	8411.6	1		Homo sapiens
4	D (X)	DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')	polymer	18	5430.5	1		Homo sapiens
5	E (Y)	DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')	polymer	15	4653.1	1		Homo sapiens
6	F (Z)	DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')	polymer	16	4822.1	1		Homo sapiens

Sequence modifications

A: 1 - 1328 (UniProt: B7ZMF2)

PDB	External Database	Details
Val 136	Ala 136	conflict
Asn 476	Ser 476	conflict
Glu 638	Lys 638	conflict
Gln 657	Lys 657	conflict
Leu 877	Ile 877	conflict
Val 1235	Ala 1235	conflict
Ser 1274	Asn 1274	conflict

B: 1 - 1451 (UniProt: Q9BXW9)

PDB	External Database	Details
Gln 654	His 654	conflict
Asn 693	Asp 693	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	337198.0
All*	Total formula weight	337198.0

*Water molecules are not included.