6V7T
Crystal structure of CTX-M-14 E166A/D240G beta-lactamase in complex with ceftazidime
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase | polymer | 264 | 27955.6 | 2 | UniProt (Q9L5C7) Pfam (PF00144) Pfam (PF13354) | Escherichia coli | |
| 2 | C, D (A, B) | ACYLATED CEFTAZIDIME | non-polymer | 469.5 | 2 | Chemie (CAZ) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 705 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 290 (UniProt: Q9L5C7)
| PDB | External Database | Details |
|---|---|---|
| Ala 166 | Glu 169 | engineered mutation |
| Gly 240 | Asp 242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55911.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 939.0 | |
| All* | Total formula weight | 56850.1 |
