6V7T

Crystal structure of CTX-M-14 E166A/D240G beta-lactamase in complex with ceftazidime

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-lactamase	polymer	264	27955.6	2	UniProt (Q9L5C7)	Escherichia coli
2	C, D (A, B)	ACYLATED CEFTAZIDIME	non-polymer		469.5	2	Chemie (CAZ)
3	E, F (A, B)	water	water		18.0	705	Chemie (HOH)

Sequence modifications

A, B: 24 - 290 (UniProt: Q9L5C7)

PDB	External Database	Details
Ala 166	Glu 169	engineered mutation
Gly 240	Asp 242	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55911.1
Non-Polymers*	Number of molecules	2
	Total formula weight	939.0
All*	Total formula weight	56850.1

*Water molecules are not included.