6V4N
Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | I, M, N, W | Neuraminidase | polymer | 448 | 50038.8 | 4 | UniProt (A0A4P8YQ63) Pfam (PF00064) UniProt (by SIFTS) (A0A1S5RAG6) In PDB | Influenza B virus | |
| 2 | A, C, D, H | Antibody Fab heavy chain | polymer | 244 | 26137.3 | 4 | Homo sapiens | ||
| 3 | B, E, G, L | Antibody Fab light chain | polymer | 214 | 23521.2 | 4 | Homo sapiens | ||
| 4 | F, K, O, R, U... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G15407YE) | |||
| 5 | J, P, Q, S, T... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 6 | M, N, W, I | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 7 | N, M | beta-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (BMA) | |||
| 8 | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
I, M, N, W: 80 - 466 (UniProt: A0A4P8YQ63)
| PDB | External Database | Details |
|---|---|---|
| Ala 19 | - | expression tag |
| Asp 20 | - | expression tag |
| Pro 21 | - | expression tag |
| His 22 | - | expression tag |
| His 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| His 26 | - | expression tag |
| His 27 | - | expression tag |
| Ser 28 | - | expression tag |
| Ser 29 | - | expression tag |
| Ser 30 | - | expression tag |
| Asp 31 | - | expression tag |
| Tyr 32 | - | expression tag |
| Ser 33 | - | expression tag |
| Asp 34 | - | expression tag |
| Leu 35 | - | expression tag |
| Gln 36 | - | expression tag |
| Arg 37 | - | expression tag |
| Val 38 | - | expression tag |
| Lys 39 | - | expression tag |
| Gln 40 | - | expression tag |
| Glu 41 | - | expression tag |
| Leu 42 | - | expression tag |
| Leu 43 | - | expression tag |
| Glu 44 | - | expression tag |
| Glu 45 | - | expression tag |
| Val 46 | - | expression tag |
| Lys 47 | - | expression tag |
| Lys 48 | - | expression tag |
| Glu 49 | - | expression tag |
| Leu 50 | - | expression tag |
| Gln 51 | - | expression tag |
| Lys 52 | - | expression tag |
| Val 53 | - | expression tag |
| Lys 54 | - | expression tag |
| Glu 55 | - | expression tag |
| Glu 56 | - | expression tag |
| Ile 57 | - | expression tag |
| Ile 58 | - | expression tag |
| Glu 59 | - | expression tag |
| Ala 60 | - | expression tag |
| Phe 61 | - | expression tag |
| Val 62 | - | expression tag |
| Gln 63 | - | expression tag |
| Glu 64 | - | expression tag |
| Leu 65 | - | expression tag |
| Arg 66 | - | expression tag |
| Lys 67 | - | expression tag |
| Arg 68 | - | expression tag |
| Gly 69 | - | expression tag |
| Ser 70 | - | expression tag |
| Leu 71 | - | expression tag |
| Val 72 | - | expression tag |
| Pro 73 | - | expression tag |
| Arg 74 | - | expression tag |
| Gly 75 | - | expression tag |
| Ser 76 | - | expression tag |
| Pro 77 | - | expression tag |
| Ser 78 | - | expression tag |
| Arg 79 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 398789.0 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 6065.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 520.6 | |
| All* | Total formula weight | 405375.3 |
