6V0S
Crystal structure of the bromodomain of human BRD9 bound to TG003
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 9 | polymer | 123 | 14249.8 | 2 | UniProt (Q9H8M2) Pfam (PF00439) | Homo sapiens (Human) | Rhabdomyosarcoma antigen MU-RMS-40.8 |
| 2 | C, D (A, B) | (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one | non-polymer | 249.3 | 2 | Chemie (EAE) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, B: 130 - 250 (UniProt: Q9H8M2)
| PDB | External Database | Details |
|---|---|---|
| Ser 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28499.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 498.7 | |
| All* | Total formula weight | 28998.2 |
