6UZ5

Solution structure of KTI55-Kringle 2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Plasminogen	polymer	87	10166.3	1	UniProt (P00747) Pfam (PF00051) In PDB	Homo sapiens (Human)
2	B	M protein	polymer	57	6799.5	1	UniProt (M4I070) Pfam (PF12107) In PDB	Streptococcus pyogenes	KTI55

Sequence modifications

A: 166 - 243 (UniProt: P00747)

PDB	External Database	Details
Tyr -7	-	expression tag
Val -6	-	expression tag
Glu -5	-	expression tag
Phe -4	-	expression tag
Ser -3	-	expression tag
Glu -2	-	expression tag
Glu -1	-	expression tag
Gly 169	Cys 188	engineered mutation
Asp 221	Glu 240	engineered mutation
Tyr 237	Leu 256	engineered mutation
Ala 244	-	expression tag
Ala 245	-	expression tag

B: 85 - 139 (UniProt: M4I070)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
Arg 105	Gln 64	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	16965.8
All*	Total formula weight	16965.8

*Water molecules are not included.