6UYN
Crystal structure of influenza A virus hemagglutinin from A/Ohio/09/2015 bound to the stalk-binding CR6261 antibody Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hemagglutinin HA1 chain | polymer | 566 | 63224.2 | 2 | UniProt (A0A6C0TB04) Pfam (PF00509) | Influenza A virus | |
| 2 | C (H) | CR6261 Fab heavy chain | polymer | 232 | 24810.0 | 1 | Homo sapiens (Human) | ||
| 3 | D (L) | CR6261 Fab light chain | polymer | 221 | 23257.8 | 1 | Homo sapiens (Human) | ||
| 4 | E (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F, H (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | I, J, K, L (A, B, H, L) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 566 (UniProt: A0A6C0TB04)
| PDB | External Database | Details |
|---|---|---|
| Asn 4 | Ile 4 | variant |
| Leu 6 | Ile 6 | variant |
| Cys 10 | Tyr 10 | variant |
| Ala 11 | Thr 11 | variant |
| Leu 12 | Phe 12 | variant |
| Ala 13 | Thr 13 | variant |
| Ala 14 | Thr 14 | variant |
| Asp 16 | Asn 16 | variant |
| Leu 544 | Val 544 | variant |
| Ile 564 | Val 564 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 174516.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 477.9 | |
| All* | Total formula weight | 175418.4 |
