6UYN

Crystal structure of influenza A virus hemagglutinin from A/Ohio/09/2015 bound to the stalk-binding CR6261 antibody Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Hemagglutinin HA1 chain	polymer	566	63224.2	2	UniProt (A0A6C0TB04) Pfam (PF00509) In PDB	Influenza A virus
2	H	CR6261 Fab heavy chain	polymer	232	24810.0	1		Homo sapiens (Human)
3	L	CR6261 Fab light chain	polymer	221	23257.8	1		Homo sapiens (Human)
4	C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7		water	water		18.0	38	Chemie (HOH)

Sequence modifications

A, B: 1 - 566 (UniProt: A0A6C0TB04)

PDB	External Database	Details
Asn 4	Ile 4	variant
Leu 6	Ile 6	variant
Cys 10	Tyr 10	variant
Ala 11	Thr 11	variant
Leu 12	Phe 12	variant
Ala 13	Thr 13	variant
Ala 14	Thr 14	variant
Asp 16	Asn 16	variant
Leu 544	Val 544	variant
Ile 564	Val 564	variant

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	174516.1
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	3
	Total formula weight	477.9
All*	Total formula weight	175418.4

*Water molecules are not included.