6UXR
Crystal structure of BAK core domain BH3-groove-dimer in complex with LysoPC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bcl-2 homologous antagonist/killer | polymer | 85 | 9500.7 | 2 | UniProt (Q16611) Pfam (PF00452) | Homo sapiens (Human) | Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7 |
| 2 | C, D (B) | [(2~{R})-2-oxidanyl-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propyl] hexadecanoate | non-polymer | 496.6 | 2 | Chemie (K6G) | |||
| 3 | E (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 4 | F, G, H, I (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 4 | Chemie (PGE) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, B: 68 - 148 (UniProt: Q16611)
| PDB | External Database | Details |
|---|---|---|
| Gly 64 | - | expression tag |
| Pro 65 | - | expression tag |
| Leu 66 | - | expression tag |
| Gly 67 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19001.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1788.2 | |
| All* | Total formula weight | 20789.6 |
