6UXO
Crystal structure of BAK core domain BH3-groove-dimer in complex with DDM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Bcl-2 homologous antagonist/killer | polymer | 85 | 9500.7 | 12 | UniProt (Q16611) Pfam (PF00452) | Homo sapiens (Human) | Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7 |
| 2 | AB, AC, CA, DC, EC... (F, I, C, J, D...) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 24 | Chemie (LMT) | |||
| 3 | BB, CB, DA, EA, FA... (F, C, J, G, D...) | SULFATE ION | non-polymer | 96.1 | 35 | Chemie (SO4) | |||
| 4 | HA, LB, QC, R, VA... (C, G, K, A, E...) | ACETATE ION | non-polymer | 59.0 | 6 | Chemie (ACT) | |||
| 5 | AA, BA, BC, CC, DB... (B, I, F, J, D...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 25 | Chemie (EDO) | |||
| 6 | AD, BD, CD, DD, ED... (C, D, E, F, G...) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 68 - 148 (UniProt: Q16611)
| PDB | External Database | Details |
|---|---|---|
| Gly 64 | - | expression tag |
| Pro 65 | - | expression tag |
| Leu 66 | - | expression tag |
| Gly 67 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 114008.3 | |
| Non-Polymers* | Number of molecules | 90 |
| Total formula weight | 17522.9 | |
| All* | Total formula weight | 131531.2 |
