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6UW9

Cryo-EM structure of the human TRPV3 K169A mutant in the presence of 2-APB, determined in lipid nanodisc

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential cation channel subfamily V member 3polymer79090670.74UniProt (Q8NET8)
Pfam (PF12796)
Pfam (PF00023)
Pfam (PF00520)
Homo sapiens (Human)TrpV3,Vanilloid receptor-like 3,VRL-3
Sequence modifications
A, B, C, D: 1 - 790 (UniProt: Q8NET8)
PDBExternal DatabaseDetails
Val 25Ile 25variant
Ala 169Lys 169engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight362682.8
All*Total formula weight362682.8
*Water molecules are not included.

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PDB entries from 2024-11-06

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